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2024
1 Cavanaugh, Dana; Urbanucci, Alfonso; Mohamed, Nihal E.; Tewari, Ashutosh K.; Figueiro, Mariana; Kyprianou, Natasha.
Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS). The Prostate 2024 s. -
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2022
2 Engedal, Kim Nikolai Hartlieb; Sønstevold, Tonje; Beese, Carsten J.; Selledurai, Sarvini; Melcher, Thea; Simensen, Julia Elisabeth; Frankel, Lisa B.; Urbanucci, Alfonso; Torgersen, Maria Lyngaas.
Measuring Autophagic Cargo Flux with Keima-Based Probes. Methods in molecular biology 2022
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3 Urbanucci, Alfonso; Engedal, Nikolai.
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Nature Biotechnology 2022
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2021
4 Cangiano, Mario; Grudniewska, Magda; Salji, Marj J.; Nykter, Matti; Jenster, Guido; Urbanucci, Alfonso; Granchi, Zoraide; Janssen, Bart; Hamilton, Graham; Leung, Hung Y; Beumer, Ines j..
Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer. Cancers 2021
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5 Kukkonen, Konsta; Taavitsainen, Sinja; Huhtala, Laura; Uusi-Makela, Joonas; Granberg, Kirsi J.; Nykter, Matti; Urbanucci, Alfonso.
Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response. Cancers 2021
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6 Nakken, Sigve; Lilleby, Wolfgang; Switlyk, Marta Daniela; Knudsen, Karen E.; Lilleby, Oscar; Zhao, Sen; Kaveh, Fatemeh; Ekstrøm, Per O.; Urbanucci, Alfonso; Hovig, Eivind.
The quandary of dna-based treatment assessment in de novo metastatic prostate cancer in the era of precision oncology. Journal of Personalized Medicine 2021 ;Volum 11.(5) s. 1-18
OUS UiO Untitled
 
7 Taavitsainen, S.; Engedal, Nikolai; Cao, S.; Handle, Florian; Erickson, A.; Prekovic, Stefan; Wetterskog, D.; Tolonen, Teemu T.; Vuorinen, E.M.; Kiviaho, A.; Nätkin, R.; Häkkinen, T.; Devlies, W.; Henttinen, S.; Kaarijärvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvälä, H.; Bläuer, M.; Cremaschi, P.; Claessens, Frank; Visakorpi, Tapio; Tammela, T.L.J.; Murtola, T.; Granberg, K.J.; Lamb, Alastair D.; Ketola, Kirsi; Mills, Ian; Attard, Gerhardt; Wang, W.; Nykter, Matti; Urbanucci, Alfonso.
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse. Nature Communications 2021 ;Volum 12.(1) s. -
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2020
8 Itkonen, Harri; Poulose, Ninu; Steele, Rebecca E.; Martin, Sara E.S.; Levine, Zebulon G.; Duveau, Damien Y.; Carelli, Ryan; Singh, Reema; Urbanucci, Alfonso; Loda, Massimo; Thomas, Craig J.; Mills, Ian Geoffrey; Walker, Suzanne.
Inhibition of O-GlcNAc transferase renders prostate cancer cells dependent on CDK9. Molecular Cancer Research 2020 ;Volum 18.(10) s. 1512-1521
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9 Kohvakka, Annika; Sattari, Mina; Shcherban, Anastasia; Annala, Matti; Urbanucci, Alfonso; Kesseli, Juha; Tammela, Teuvo L. J.; Kivinummi, Kati K.; Latonen, Leena; Nykter, Matti; Visakorpi, Tapio.
AR and ERG drive the expression of prostate cancer specific long noncoding RNAs. Oncogene 2020 ;Volum 39. s. 5241-5251
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10 Lavelle, Timothy J; Alver, Tine Norman; Heintz, Karen Marie; Wernhoff, Patrik; Nygaard, Vegard; Nakken, Sigve; Øy, Geir Frode; Bøe, Sigurd; Urbanucci, Alfonso; Hovig, Eivind.
Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes. Cancers 2020 ;Volum 12.(7) Suppl. 1719 s. 1-20
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11 Pace, Marta; Falappa, Matteo; Freschi, Andrea; Balzani, Edoardo; Berteotti, Chiara; Martire, Viviana Lo; Kaveh, Fatemeh; Hovig, Eivind; Zoccoli, Giovanna; Amici, Roberto; Cerri, Matteo; Urbanucci, Alfonso; Tucci, Valter.
Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors. JCI Insight 2020 ;Volum 5.(12) s. 1-18
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2019
12 Braadland, Peder Rustøen; Ramberg, Håkon Andre; Grytli, Helene Hartvedt; Urbanucci, Alfonso; Nielsen, Heidi Kristin; Guldvik, Ingrid Jenny; Engedahl, Andreas; Ketola, Kirsi; Wanzhong, Wang; Svindland, Aud; Mills, Ian Geoffrey; Bjartell, Anders; Tasken, Kristin Austlid.
The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells. Molecular Cancer Research 2019 ;Volum 17.(11) s. 2154-2168
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13 Braadland, Peder Rustøen; Urbanucci, Alfonso.
Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer. Endocrine-Related Cancer 2019 ;Volum 26.(4) s. R211-R235
UiO OUS Untitled
 
14 Handle, Florian; Prekovic, Stefan; Helsen, Christine; van den Broeck, Thomas; Smeets, Elien; Moris, Lisa; Eerlings, Roy; El Kharraz, Sarah; Urbanucci, Alfonso; Mills, Ian Geoffrey; Joniau, Steven; Attard, Gerhardt; Claessens, Frank.
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells. Scientific Reports 2019 ;Volum 9.(13786) s. 1-11
OUS UiO Untitled
 
15 Itkonen, Harri; Urbanucci, Alfonso; Sara ES, Martin; Khan, Aziz; Mathelier, Anthony; Thiede, Bernd; Walker, Suzanne; Mills, Ian Geoffrey.
High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. Theranostics 2019 ;Volum 9.(8) s. 2183-2197
UiO OUS Untitled
 
2018
16 Gerhauser, Clarissa; Favero, Francesco; Risch, Thomas; Simon, Ronald; Feuerbach, Lars; Assenov, Yassen; Heckmann, Doreen; Sidiropoulos, Nikos; Waszak, Sebastian M.; Hübschmann, Daniel; Urbanucci, Alfonso; Girma, Etsehiwot G.; Kuryshev, Vladimir; Klimczak, Leszek J.; Saini, Natalie; Stütz, Adrian M.; Weichenhan, Dieter; Böttcher, Lisa-Marie; Toth, Reka; Hendriksen, Josephine D.; Koop, Christina; Lutsik, Pavlo; Matzk, Sören; Warnatz, Hans-Jörg; Amstislavskiy, Vyacheslav; Feuerstein, Clarissa; Raeder, Benjamin; Bogatyrova, Olga; Schmitz, Eva-Maria; Hube-Magg, Claudia; Kluth, Martina; Huland, Hartwig; Graefen, Markus; Lawerenz, Chris; Henry, Gervaise H.; Yamaguchi, Takafumi N.; Malewska, Alicia; Meiners, Jan; Schilling, Daniela; Reisinger, Eva; Eils, Roland; Schlesner, Matthias; Strand, Douglas W.; Bristow, Robert G.; Boutros, Paul C.; von Kalle, Christof; Gordenin, Dmitry; Sültmann, Holger; Brors, Benedikt; Sauter, Guido; Plass, Christoph; Yaspo, Marie-Laure; Korbel, Jan O.; Schlomm, Thorsten; Weischenfeldt, Joachim.
Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories. Cancer Cell 2018 ;Volum 34.(6) s. 996-1011.e8
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2017
17 Barfeld, Stefan Jörg; Urbanucci, Alfonso; Itkonen, Harri; Fazli, Ladan; Hicks, Jessica L; Thiede, Bernd; Rennie, Paul S.; Yegnasubramanian, Srinivasan; DeMarzo, Angelo M.; Mills, Ian Geoffrey.
c-Myc antagonises the transcriptional activity of the androgen receptor in prostate cancer affecting key gene networks. EBioMedicine 2017 ;Volum 18. s. 83-93
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18 Itkonen, Harri; Brown, Michael; Urbanucci, Alfonso; Tredwell, Gregory; Lau, Chung Ho; Barfeld, Stefan Jörg; Hart, Claire; Guldvik, Ingrid Jenny; Takhar, Mandeep; Heemers, Hannelore V.; Erho, Nicholas; Bloch, Katarzyna; Davicioni, Elai; Derua, Rita; Waelkens, Etienne; Mohler, James L.; Clarke, Noel; Swinnen, Johan V.; Keun, Hector C.; Rekvig, Ole Petter; Mills, Ian Geoffrey.
Lipid degradation promotes prostate cancer cell survival. OncoTarget 2017 ;Volum 8.(24) s. 38264-38275
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19 Kivinummi, Kati K.; Urbanucci, Alfonso; Leinonen, Kaisa; Tammela, Teuvo L.J.; Annala, Matti; Isaacs, William B.; Bova, G. Steven; Nykter, Matti; Visakorpi, Tapio.
The expression of AURKA is androgen regulated in castration-resistant prostate cancer. Scientific Reports 2017 ;Volum 7:17978.(1) s. 1-11
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20 Urbanucci, Alfonso; Barfeld, Stefan Jörg; Kytölä, Ville; Itkonen, Harri; Coleman, Ilsa M.; Vodák, Daniel; Sjöblom, Liisa; Sheng, Xia; Minner, Sarah; Burdelski, Christoph; Kivinummi, Kati K.; Kohvakka, Annika; Kregel, Steven; Takhar, Mandeep; Alshalalfa, Mohammed; Davicioni, Elai; Erho, Nicholas; Lloyd, Paul; Karnes, R. Jeffrey; Ross, Ashley E.; Schaeffer, Edward M.; Vander Griend, Donald J; Knapp, Stefan; Corey, Eva; Feng, Felix Y.; Nelson, Peter S.; Saatcioglu, Fahri; Knudsen, Karen E.; Tammela, Teuvo L.J.; Sauter, Guido; Schlomm, Thorsten; Nykter, Matti; Visakorpi, Tapio; Mills, Ian Geoffrey.
Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer. Cell reports 2017 ;Volum 19.(10) s. 2045-2059
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21 Urbanucci, Alfonso; Mills, Ian Geoffrey.
Bromodomain-containing proteins in prostate cancer. Molecular and Cellular Endocrinology 2017 ;Volum 17. s. 31-40
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22 Zuber, Verena; Bettella, Francesco; Witoelar, Aree; Andreassen, Ole Andreas; Mills, Ian Geoffrey; Urbanucci, Alfonso.
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer. BMC Genomics 2017 ;Volum 18:270. s. 1-11
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2016
23 Fiorito, Elisa; Sharma, Yogita; Gilfillan, Siv; Wang, Shixiong; Singh, Sachin Kumar; Somisetty, Venkata Satheesh; Madhumohan, Katika; Urbanucci, Alfonso; Thiede, Bernd; Mills, Ian Geoffrey; Rodriguez, Antoni Hurtado.
CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions. Nucleic Acids Research (NAR) 2016 ;Volum 44. s. 10588-10602
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24 McNair, C; Urbanucci, Alfonso; Comstock, CES; Augello, MA; Goodwin, JF; Launchbury, R; Zhao, SG; Schiewer, MJ; Ertel, A; Karnes, J; Davicioni, E; Wang, L; Wang, Q; Mills, Ian Geoffrey; Feng, FY; Li, W; Carroll, JS; Knudsen, KE.
Cell cycle-coupled expansion of AR activity promotes cancer progression. Oncogene 2016 ;Volum 36.(12) s. 1655-1668
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25 Tekpli, Xavier; Urbanucci, Alfonso; Hashim, Adnan; Vågbø, Cathrine Broberg; Lyle, Robert; Kringen, Marianne K.; Staff, Anne Cathrine; Dybedal, Ingunn; Mills, Ian Geoffrey; Klungland, Arne; Staerk, Judith.
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells. Epigenetics & Chromatin 2016 ;Volum 9.
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2015
26 Barfeld, Stefan; Fazli, Ladan; Persson, Margareta; Marjavaara, Lisette; Urbanucci, Alfonso; Kaukoniemi, Kirsi M.; Rennie, Paul S.; Ceder, Yvonne; Chabes, Andrei; Visakorpi, Tapio; Mills, Ian Geoffrey.
Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer. OncoTarget 2015 ;Volum 6.(14) s. 12587-12602
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27 Khanna, Anchit; Rane, Jayant K.; Kivinummi, Kati K.; Urbanucci, Alfonso; Helenius, Merja A.; Tolonen, Teemu T.; Saramäki, Outi R.; Latonen, Leena; Manni, Visa; Pimanda, John E.; Maitland, Norman J.; Westermarck, Jukka; Visakorpi, Tapio.
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations. OncoTarget 2015 ;Volum 6.(23) s. 19661-19670
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28 Lund, Kaja; Dembinski, Jennifer Lynn; Solberg, Nina; Urbanucci, Alfonso; Mills, Ian Geoffrey; Krauss, Stefan.
Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLOS ONE 2015 ;Volum 10.(4)
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2014
29 Barfeld, Stefan; Itkonen, Harri; Urbanucci, Alfonso; Mills, Ian Geoffrey.
Androgen-regulated metabolism and biosynthesis in prostate cancer. Endocrine-Related Cancer 2014 ;Volum 21.(4) s. T57-T66
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2013
30 Lehmusvaara, Saara; Erkkilä, Timo; Urbanucci, Alfonso; Jalava, Sanni; Seppälä, Janne; Kaipia, Antti; Kujala, Paula; Lähdesmäki, Harri; Tammela, Teuvo L.J.; Visakorpi, Tapio.
Goserelin and bicalutamide treatments alter the expression of microRNAs in the prostate. The Prostate 2013 ;Volum 73.(1) s. 101-112
UiO Untitled