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Viser treff 1-26 av 26

2017
1 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel. Data in Brief 2017 ;Volum 12. s. 18-21
NTNU Untitled
 
2 Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit.
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay. Analytical Biochemistry 2017 ;Volum 523. s. 10-16
NTNU Untitled
 
3 Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Investigation of Heck coupling on 6-bromo[2,3-d]thienopyrimidines for construction of new EGFR inhibitor lead structures. RSC Advances 2017 ;Volum 7.(30) s. 18569-18577
NTNU Untitled
 
2016
4 Bugge, Steffen; Buene, Audun Formo; Jurisch-Yaksi, Nathalie; Moen, Ingri Ullestad; Skjønsfjell, Ellen Martine; Sundby, Eirik; Hoff, Bård Helge.
Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties. European Journal of Medicinal Chemistry 2016 ;Volum 107. s. 255-274
NTNU Untitled
 
2015
5 Buene, Audun Formo; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Synthesis of amide containing thienopyrimidines. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
NTNU Untitled
 
6 Buene, Audun Formo.
Synthesis of Thieno[2,3-d]pyrimidine-Based EGFR-TK Inhibitors with Improved Solubility and Metabolic Stability. : NTNU, IKJ 2015 300 s.
NTNU Untitled
 
7 Bugge, Steffen.
Development of Thienopyrimidines as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Trondheim: NTNU 2015 (ISBN 978-82-326-1046-4) ;Volum 2015.296 s. Doktoravhandlinger ved NTNU(195)
NTNU Untitled
 
8 Bugge, Steffen; Moen, Ingri Ullestad; Sylte, Kent-Ove Kragseth; Sundby, Eirik; Hoff, Bård Helge.
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors. European Journal of Medicinal Chemistry 2015 ;Volum 94. s. 175-194
NTNU Untitled
 
9 Hoff, Bård Helge; Sundby, Eirik; Han, Jin; Bugge, Steffen.
Thieno- and Pyrrolo[2,3-d]pyrimidine base EGFR inhibitors and their ADME profile. , International Symposium in Synthetic and Medicinal Chemistry; 2015-11-15 - 2015-11-18
NTNU Untitled
 
10 Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Optimization of Heck reaction on the thienopyrimidine scaffold. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11
NTNU Untitled
 
2014
11 Bugge, Steffen; Kaspersen, Svein Jacob; Larsen, Synne; Nonstad, Unni; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge.
Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor. European Journal of Medicinal Chemistry 2014 ;Volum 75. Suppl. ja s. 354-374
NTNU Untitled
 
12 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Structure-activity study leading to the identification of a highly active thienopyrimidine based EGFR inhibitor. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12
NTNU Untitled
 
13 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Use of the thienopyrimidine scaffold for development of new EGFR-TK inhibitors. Kinase 2014: Past, Present and Beyond. 19-20 May 2014; 2014-05-19 - 2014-05-20
NTNU Untitled
 
14 Bugge, Steffen; Skjønsfjell, Ellen Martine; Willumsen, Fredrik Bysting; Sundby, Eirik; Hoff, Bård Helge.
Improved and Scalable Preparation of 6-Bromo-4-Chlorothieno[2,3-d]Pyrimidine. Chemistry of Heterocyclic Compounds 2014 ;Volum 50.(8) s. 1177-1187
NTNU Untitled
 
15 Kaspersen, Svein Jacob; Han, Jin; Nørsett, Kristin; Rydså, Line; Kjøbli, Eli; Bugge, Steffen; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge.
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4- amines as highly potent EGFR-TK inhibitors with Src-family activity. European Journal of Pharmaceutical Sciences 2014 ;Volum 59.(1) Suppl. yes s. 69-82
NTNU Untitled
 
16 Ullestad Moen, Ingri; Kragseth Sylte, Kent-Ove; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Fragment based approach in the search for new kinase inhibitors. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12
NTNU Untitled
 
2013
17 Bugge, Steffen; Kaspersen, Svein Jacob; Lange, Sandra; Sundby, Eirik; Hoff, Bård Helge.
Structure-activity study of thienopyrimidines as EGFR tyrosine kinase inhibitors. Det 28. Organisk kjemiske vintermøte; 2013-01-10 - 2013-01-13
NTNU Untitled
 
18 Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Pyrrolopyrimidines as Potential EGFR Kinase Inhibitors. The 24. International Society of Heterocyclic Chemistry Congress; 2013-09-08 - 2013-09-13
NTNU Untitled
 
19 Skjønsfjell, Ellen Martine; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Investigation and scale up of the synthesis of 6-bromo-4-chlorothieno[2,3-d]pyrimidine. Det 28. Organisk kjemiske vintermøte; 2013-01-10 - 2013-01-13
NTNU Untitled
 
2012
20 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Route selection in synthesis of thienopyrimidines. Organisk kjemisk vintermøte 2012; 2012-01-12 - 2012-01-15
NTNU Untitled
 
21 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines. Tetrahedron 2012 ;Volum 68.(45) s. 9226-9233
NTNU Untitled
 
22 Zolubas, Giedrius; Bugge, Steffen; Thvedt, Thor Håkon Krane; Sundby, Eirik; Hoff, Bård Helge.
Building blocks for thienopyrimidines synthezised using microwave heating. Organisk kjemisk vintermøte; 2012-01-12 - 2012-01-15
NTNU Untitled
 
2011
23 Bugge, Steffen.
Bruk av koblingskjemi i fremstilling av bioaktive tienopyrimidiner. Trondheim: NTNU, IKJ 2011 297 s.
NTNU Untitled
 
24 Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge.
Thieno- and pyrrolopyrimidines as potential kinase inhibitors. Organisk Kjemisk Vintermøte; 2011-01-06 - 2011-01-09
NTNU Untitled
 
25 Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Pyrrolo- and thienopyrimidines as potential kinase inhibitors. 17. European Symposium on Organic Chemistry; 2011-07-10 - 2011-07-15
NTNU Untitled
 
26 Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge.
Pyrrolo-and thienopyrimidines as potential kinase inhibitors. The 2011 PhD Candidate seminar on medicinal technology; 2011-05-26 - 2011-05-26
NTNU Untitled