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English
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2017
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1. |
Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit. Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel. Data in Brief 2017 ;Volum 12. s. 18-21 NTNU
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2. |
Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit. On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay. Analytical Biochemistry 2017 ;Volum 523. s. 10-16 NTNU
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3. |
Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Investigation of Heck coupling on 6-bromo[2,3-d]thienopyrimidines for construction of new EGFR inhibitor lead structures. RSC Advances 2017 ;Volum 7.(30) s. 18569-18577 NTNU
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2016
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4. |
Bugge, Steffen; Buene, Audun Formo; Jurisch-Yaksi, Nathalie; Moen, Ingri Ullestad; Skjønsfjell, Ellen Martine; Sundby, Eirik; Hoff, Bård Helge. Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties. European Journal of Medicinal Chemistry 2016 ;Volum 107. s. 255-274 NTNU
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2015
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5. |
Buene, Audun Formo; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Synthesis of amide containing thienopyrimidines. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11 NTNU
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6. |
Buene, Audun Formo. Synthesis of Thieno[2,3-d]pyrimidine-Based EGFR-TK Inhibitors with Improved Solubility and Metabolic Stability. : NTNU, IKJ 2015 300 s. NTNU
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7. |
Bugge, Steffen. Development of Thienopyrimidines as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Trondheim: NTNU 2015 (ISBN 978-82-326-1046-4) ;Volum 2015.296 s. Doktoravhandlinger ved NTNU(195) NTNU
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8. |
Bugge, Steffen; Moen, Ingri Ullestad; Sylte, Kent-Ove Kragseth; Sundby, Eirik; Hoff, Bård Helge. Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors. European Journal of Medicinal Chemistry 2015 ;Volum 94. s. 175-194 NTNU
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9. |
Hoff, Bård Helge; Sundby, Eirik; Han, Jin; Bugge, Steffen. Thieno- and Pyrrolo[2,3-d]pyrimidine base EGFR inhibitors and their ADME profile. , International Symposium in Synthetic and Medicinal Chemistry; 2015-11-15 - 2015-11-18 NTNU
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10. |
Willumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Optimization of Heck reaction on the thienopyrimidine scaffold. Organisk kjemisk vintermøte OKV 30; 2015-01-08 - 2015-01-11 NTNU
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2014
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11. |
Bugge, Steffen; Kaspersen, Svein Jacob; Larsen, Synne; Nonstad, Unni; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge. Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor. European Journal of Medicinal Chemistry 2014 ;Volum 75. Suppl. ja s. 354-374 NTNU
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12. |
Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. Structure-activity study leading to the identification of a highly active thienopyrimidine based EGFR inhibitor. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12 NTNU
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13. |
Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. Use of the thienopyrimidine scaffold for development of new EGFR-TK inhibitors. Kinase 2014: Past, Present and Beyond. 19-20 May 2014; 2014-05-19 - 2014-05-20 NTNU
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14. |
Bugge, Steffen; Skjønsfjell, Ellen Martine; Willumsen, Fredrik Bysting; Sundby, Eirik; Hoff, Bård Helge. Improved and Scalable Preparation of 6-Bromo-4-Chlorothieno[2,3-d]Pyrimidine. Chemistry of Heterocyclic Compounds 2014 ;Volum 50.(8) s. 1177-1187 NTNU
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15. |
Kaspersen, Svein Jacob; Han, Jin; Nørsett, Kristin; Rydså, Line; Kjøbli, Eli; Bugge, Steffen; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge. Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4- amines as highly potent EGFR-TK inhibitors with Src-family activity. European Journal of Pharmaceutical Sciences 2014 ;Volum 59.(1) Suppl. yes s. 69-82 NTNU
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16. |
Ullestad Moen, Ingri; Kragseth Sylte, Kent-Ove; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Fragment based approach in the search for new kinase inhibitors. Organisk kjemisk vintermøte 2014; 2014-01-09 - 2014-01-12 NTNU
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2013
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17. |
Bugge, Steffen; Kaspersen, Svein Jacob; Lange, Sandra; Sundby, Eirik; Hoff, Bård Helge. Structure-activity study of thienopyrimidines as EGFR tyrosine kinase inhibitors. Det 28. Organisk kjemiske vintermøte; 2013-01-10 - 2013-01-13 NTNU
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18. |
Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Pyrrolopyrimidines as Potential EGFR Kinase Inhibitors. The 24. International Society of Heterocyclic Chemistry Congress; 2013-09-08 - 2013-09-13 NTNU
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19. |
Skjønsfjell, Ellen Martine; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Investigation and scale up of the synthesis of 6-bromo-4-chlorothieno[2,3-d]pyrimidine. Det 28. Organisk kjemiske vintermøte; 2013-01-10 - 2013-01-13 NTNU
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2012
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20. |
Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. Route selection in synthesis of thienopyrimidines. Organisk kjemisk vintermøte 2012; 2012-01-12 - 2012-01-15 NTNU
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21. |
Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines. Tetrahedron 2012 ;Volum 68.(45) s. 9226-9233 NTNU
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22. |
Zolubas, Giedrius; Bugge, Steffen; Thvedt, Thor Håkon Krane; Sundby, Eirik; Hoff, Bård Helge. Building blocks for thienopyrimidines synthezised using microwave heating. Organisk kjemisk vintermøte; 2012-01-12 - 2012-01-15 NTNU
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2011
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23. |
Bugge, Steffen. Bruk av koblingskjemi i fremstilling av bioaktive tienopyrimidiner. Trondheim: NTNU, IKJ 2011 297 s. NTNU
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24. |
Bugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. Thieno- and pyrrolopyrimidines as potential kinase inhibitors. Organisk Kjemisk Vintermøte; 2011-01-06 - 2011-01-09 NTNU
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25. |
Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Pyrrolo- and thienopyrimidines as potential kinase inhibitors. 17. European Symposium on Organic Chemistry; 2011-07-10 - 2011-07-15 NTNU
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26. |
Kaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. Pyrrolo-and thienopyrimidines as potential kinase inhibitors. The 2011 PhD Candidate seminar on medicinal technology; 2011-05-26 - 2011-05-26 NTNU
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