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2024
1 Olsen, Thomas; Stolt, Emma Theresia Kjelland; Øvrebø, Bente; Elshorbagy, Amany; Tore, Elena C.; Lee-Ødegård, Sindre; Troensegaard, Hannibal; Johannessen, Hanna; Doeland, Beate; Vo, Anna A.D; Dahl, Anja Falkenhaug; Svendsen, Karianne; Thoresen, Magne; Refsum, Helga; Rising, Russell; Barvíková, Kristýna; Van Greevenbroek, Marleen M.J.; Kozich, Viktor; Retterstøl, Kjetil; Vinknes, Kathrine Jørgensen.
Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial. Journal of Translational Medicine 2024 ;Volume 22.(1)
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2023
2 Elshorbagy, Amany; Bastani, Nasser Ezzatkhah; Lee-Ødegård, Sindre; Øvrebø, Bente; Haj Yasein, Nadia; Svendsen, Karianne; Turner, Cheryl; Refsum, Helga; Vinknes, Kathrine Jørgensen; Olsen, Thomas.
Correction to: The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression (Amino Acids, (2022), 10.1007/s00726-022-03229-2). Amino Acids 2023 ;Volume 55. p. 547-548
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3 Fung, Erik; Ng, Kwan Hung; Kwok, Timothy; Lui, Leong-Ting; Palaniswamy, Saranya; Chan, Queenie; Lim, Lee-Ling; Wiklund, Petri; Xie, Suyi; Turner, Cheryl; Elshorbagy, Amany K.; Refsum, Helga; Leung, Jason C. S.; Kong, Alice P. S.; Chan, Juliana C. N.; Järvelin, Marjo-Riitta; Woo, Jean.
Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study. Biomolecules 2023 ;Volume 13.(8) p. -
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4 Grande, Giulia; Hooshmand, Babak; Vetrano, Davide Liborio; Smith, David A; Refsum, Helga; Fratiglioni, Laura; Ljungman, Petter; Wu, Jing; Bellavia, Andrea; Eneroth, Kristina; Bellander, Tom; Rizzuto, Debora.
Association of Long-term Exposure to Air Pollution and Dementia Risk: The Role of Homocysteine, Methionine, and Cardiovascular Burden. Neurology 2023 ;Volume 101.(12) p. E1231-E1240
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5 Turner, Cheryl; Refsum, Helga; Bastani, Nasser Ezzatkhah.
Determination of underivatized amino acids in human plasma using ion pair liquid chromatography/tandem mass spectrometry. Journal of chromatography. B 2023 ;Volume 1229. p. 1-9
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6 Tore, Elena C.; Eussen, Simone; Bastani, Nasser Ezzatkhah; Dagnelie, Pieter; Elshorbagy, Amany K; Grootswagers, Pol; Kozich, Viktor; Olsen, Thomas; Refsum, Helga; Retterstøl, Kjetil; Stehouwer, Coen D. A.; Stolt, Emma Theresia Kjelland; Vinknes, Kathrine Jørgensen; Van Greevenbroek, Marleen M.J..
The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study. Journal of Nutrition 2023 ;Volume 153.(7) p. 2027-2040
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7 Vinknes, Kathrine Jørgensen; Olsen, Thomas; Zare, Hasse Khiabani; Bastani, Nasser Ezzatkhah; Stolt, Emma Theresia Kjelland; Dahl, Anja Falkenhaug; Cox, Roger D.; Refsum, Helga; Retterstøl, Kjetil; Åsberg, Anders; Elshorbagy, Amany.
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study. Diabetes, obesity and metabolism 2023 ;Volume 25.(11) p. 3161-3170
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2022
8 Bastani, Nasser Ezzatkhah; Refsum, Helga; Olsen, Thomas; Vinknes, Kathrine Jørgensen; Retterstøl, Kjetil; Zare, Hasse Khiabani.
Determination of plasma thiols using LC-MS/MS: Cysteine-lowering treatment with mesna against obesity: Preliminary results from a phase I dose-finding stud. Throne Holst; 2022-04-12 - 2022-04-12
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9 Elshorbagy, Amany; Bastani, Nasser Ezzatkhah; Lee-Ødegård, Sindre; Øvrebø, Bente; Haj Yasein, Nadia; Svendsen, Karianne; Turner, Cheryl; Refsum, Helga Margaretha; Vinknes, Kathrine Jørgensen; Olsen, Thomas.
The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression. Amino Acids 2022 p. -
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10 Elshorbagy, Amany K.; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga; Kwok, Timothy.
The association of serum sulfur amino acids and related metabolites with incident diabetes: a prospective cohort study. European Journal of Nutrition 2022 ;Volume 61. p. 3161-3173
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11 Nichenametla, Sailendra N.; Mattocks, Dwight A.L.; Cooke, Diana; Midya, Vishal; Malloy, Virginia L.; Mansilla, Wilfredo; Øvrebø, Bente; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Sokolova, Jitka; Pavlikova, Marketa; Richie Jr., John P.; Shoveller, Anna K.; Refsum, Helga; Olsen, Thomas; Vinknes, Kathrine Jørgensen; Kozich, Viktor; Ables, Gene P..
Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism. Aging Cell 2022 ;Volume 21.(12) p. -
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12 Smith, David; Sobczyńska-Malefora, Agata; Green, Ralph; Reynolds, Edward H; Refsum, Helga.
Mandatory food fortification with folic acid. The Lancet Global Health 2022 ;Volume 10.(10) p. e1389-
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13 Su, Yi; Elshorbagy, Amany; Turner, Cheryl; Refsum, Helga; Kwok, Timothy.
The Association of Circulating Amino Acids and Dietary Inflammatory Potential with Muscle Health in Chinese Community-Dwelling Older People. Nutrients 2022 ;Volume 14.(12) p. -
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14 Tore, Elena C.; Elshorbagy, Amany K.; Bakers, Frans CH; Brouwers, Marin C.G.J.; Dagnelie, Pieter; Eussen, Simone J.; Jansen, Jacobus F.A.; Kooi, M. Eline; Kusters, Yvo H.A.M.; Meex, Steven JR; Olsen, Thomas; Refsum, Helga; Retterstøl, Kjetil; Schalkwijk, Casper G.; Stehouwer, Coen D.A.; Vinknes, Kathrine Jørgensen; Van Greevenbroek, Marleen M.J..
Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European Journal of Nutrition 2022 p. -
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15 Wu, Yuanyuan; Smith, A. David; Bastani, Nasser Ezzatkhah; Refsum, Helga; Kwok, Timothy.
The dihydrofolate reductase 19-bp deletion modifies the beneficial effect of B-vitamin therapy in mild cognitive impairment: Pooled study of two randomized placebo-controlled trials. Human Molecular Genetics 2022 ;Volume 31.(7) p. 1151-1158
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2021
16 Alshahawy, Rasha; Habachi, Nihal El; Allam, Eman; Jernerén, Fredrik; Refsum, Helga; Elshorbagy, Amany K.
Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults. Nutrition - The International Journal of Applied and Basic Nutritional Sciences 2021 ;Volume 90. p. -
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17 Elkafrawy, Hagar; Mehanna, Radwa; Ali, Fayrouz; Barghash, Ayman; Dessouky, Iman; Jernerén, Fredrik; Turner, Cheryl; Refsum, Helga; Elshorbagy, Amany.
Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults. Amino Acids 2021 ;Volume 53. p. 1623-1634
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18 Jakubowski, Hieronim; Zioła-Frankowska, Anetta; Frankowski, Marcin; Perła-Kaján, Joanna; Refsum, Helga; De Jager, Celeste A.; Smith, A. David.
B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment. Journal of Alzheimer's Disease 2021 ;Volume 84.(3) p. 1039-1055
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19 Olsen, Thomas; Øvrebø, Bente; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga; Vinknes, Kathrine.
Effects of short-term methionine and cysteine restriction and enrichment with polyunsaturated fatty acids on oral glucose tolerance, plasma amino acids, fatty acids, lactate and pyruvate: results from a pilot study. BMC Research Notes 2021 ;Volume 14.(43) p. -
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20 Perła-Kaján, Joanna; Włoczkowska, Olga; Zioła-Frankowska, Anetta; Frankowski, Marcin; Smith, A. David; de Jager, Celeste; Refsum, Helga; Jakubowski, Hieronim.
Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment. Journal of Alzheimer's Disease 2021 ;Volume 81.(3) p. 1211-1229
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21 Smith, A. David; Jernerén, Fredrik; Refsum, Helga.
ω-3 fatty acids and their interactions. American Journal of Clinical Nutrition 2021 ;Volume 113.(4) p. 775-778
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22 Smith, A.D.; Refsum, Helga.
Homocysteine – from disease biomarker to disease prevention.. Journal of Internal Medicine 2021 ;Volume 290.(4) p. 826-854
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23 Stolt, Emma Theresia Kjelland; Olsen, Thomas; Elshorbagy, Amany; Kozich, Viktor; Van Greevenbroek, Marleen M.J.; Øvrebø, Bente; Thoresen, Magne; Refsum, Helga; Retterstøl, Kjetil; Vinknes, Kathrine.
Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements. Journal of Translational Medicine 2021 ;Volume 19.
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24 Vinknes, Kathrine; Refsum, Helga; Turner, Cheryl; Khaw, Kay-Tee; Wareham, Nicholas J.; Forouhi, Nita G.; Imamura, Fumiaki.
Plasma Sulfur Amino Acids and Risk of Cerebrovascular Diseases: A Nested Case-Control Study in the EPIC-Norfolk Cohort. Stroke 2021 ;Volume 52.(1) p. 172-180
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25 Włoczkowska, Olga; Perła-Kaján, Joanna; Smith, A. David; de Jager, Celeste; Refsum, Helga; Jakubowski, Hieronim.
Anti-N-homocysteine-protein autoantibodies are associated with impaired cognition. Alzheimer's and Dementia: Translational Research and Clinical Interventions 2021 ;Volume 7.(1) p. 1-10
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26 Wu, Y.; Smith, A.D.; Refsum, H.; Kwok, Timothy.
Effectiveness of B Vitamins and Their Interactions with Aspirin in Improving Cognitive Functioning in Older People with Mild Cognitive Impairment: Pooled Post-Hoc Analyses of Two Randomized Trials. The Journal of Nutrition, Health & Aging 2021 ;Volume 25. p. 1154-1160
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2020
27 Calderón-Larranãga, Amaia; Saadeh, Marguerita; Hooshmand, Babak; Refsum, Helga; Smith, A. David; Marengoni, Alessandra; Vetrano, Davide L..
Association of Homocysteine, Methionine, and MTHFR 677C>T Polymorphism with Rate of Cardiovascular Multimorbidity Development in Older Adults in Sweden. JAMA Network Open 2020 ;Volume 3.(5) p. 1-14
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28 Elshorbagy, Amany; Graham, Ian; Refsum, Helga.
Body mass index determines the response of plasma sulfur amino acids to methionine loading. Biochimie 2020 ;Volume 173. p. 107-113
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29 Henjum, Sigrun; Manger, Mari Skar; Hampel, Daniela; Brantsæter, Anne Lise; Shahab-Ferdows, Setareh; Bastani, Nasser Ezzatkhah; Strand, Tor A; Refsum, Helga; Allen, Lindsay H..
Vitamin B12 concentrations in milk from Norwegian women during the six first months of lactation. European Journal of Clinical Nutrition 2020 ;Volume 74.(5) p. 749-756
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30 Lee-Ødegård, Sindre; Gulseth, Hanne Løvdal; Langleite, Torgrim Mikal; Norheim, Frode; Olsen, Thomas; Refsum, Helga; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A.
Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men. Diabetologia 2020 ;Volume 64. p. 410-423
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31 Olsen, Thomas; Sollie, Ove; Nurk, Eha; Turner, Cheryl; Jernerén, Fredrik; Ivy, John L.; Vinknes, Kathrine; Clauss, Matthieu; Refsum, Helga Margaretha; Jensen, Jørgen.
Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists. Frontiers in Physiology 2020 p. -
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32 Olsen, Thomas; Turner, Cheryl; Øvrebø, Bente; Bastani, Nasser Ezzatkhah; Refsum, Helga; Vinknes, Kathrine.
Postprandial effects of a meal low in sulfur amino acids and high in polyunsaturated fatty acids compared to a meal high in sulfur amino acids and saturated fatty acids on stearoyl CoA-desaturase indices and plasma sulfur amino acids: a pilot study. BMC Research Notes 2020 ;Volume 13. p. -
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33 Olsen, Thomas; Øvrebø, Bente; Haj Yasein, Nadia; Lee-Ødegård, Sindre; Svendsen, Karianne; Hjorth, Marit; Bastani, Nasser Ezzatkhah; Norheim, Frode; Drevon, Christian A; Refsum, Helga Margaretha; Vinknes, Kathrine.
Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study. Journal of Translational Medicine 2020 ;Volume 18.(122) p. -
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34 Pérez, Laura M.; Hooshmand, Babak; Mangialasche, Francesca; Mecocci, Patrizia; Smith, A David; Refsum, Helga; Inzitari, Marco; Fratiglioni, Laura; Rizzuto, Debora; Calderón-Larrañaga, Amaia.
Glutathione Serum Levels and Rate of Multimorbidity Development in Older Adults. The journals of gerontology. Series A, Biological sciences and medical sciences 2020 ;Volume 75.(6) p. 1089-1094
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2019
35 Hanvold, Susanna; Vinknes, Kathrine; Løken, Elin Bjørge; Hjartåker, Anette; Klungsøyr, Ole; Birkeland, Eline; Risstad, Hilde; Gulseth, Hanne Løvdal; Refsum, Helga; Aas, Anne-Marie.
Does Lifestyle Intervention After Gastric Bypass Surgery Prevent Weight Regain? A Randomized Clinical Trial. Obesity Surgery 2019 ;Volume 29.(11) p. 3419-3431
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36 Hooshmand, Babak; Refsum, Helga; Smith, A David; Kalpouzos, Gregoria; Mangialasche, Francesca; Von Arnim, Christine A.F.; Kåreholt, Ingemar; Kivipelto, Miia; Fratiglioni, Laura.
Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia. JAMA psychiatry 2019 ;Volume 76.(11) p. 1198-1205
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37 Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A David; Turner, Cheryl; Palmblad, Jan; Eriksdotter, Maria; Hjorth, Erik; Faxen-Irving, Gerd; Wahlund, Lars-Olof; Schultzberg, Marianne; Basun, Hans; Freund-Levi, Yvonne.
Homocysteine status modifies the treatment effect of omega-3 fatty acids on cognition in a randomized clinical trial in mild to moderate Alzheimer's disease: The OmegAD Study. Journal of Alzheimer's Disease 2019 ;Volume 69.(1) p. 189-197
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38 Lee-Ødegård, Sindre; Olsen, Thomas; Vinknes, Kathrine; Refsum, Helga; Gulseth, Hanne Løvdal; Birkeland, Kåre I.; Drevon, Christian A.
Plasma Sulphur-Containing Amino Acids, Physical Exercise and Insulin Sensitivity in Overweight Dysglycemic and Normal Weight Normoglycemic Men. Nutrients 2019 ;Volume 11.(1) p. -
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39 Olsen, Thomas; Vinknes, Kathrine; Blomhoff, Rune; Lysne, Vegard; Midttun, Øivind; Dhar, Indu; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Drevon, Christian A; Refsum, Helga; Nygård, Ottar.
Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease. European Journal of Nutrition 2019
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40 Smith, A. David; Refsum, Helga; Miller, Joshua W..
Dietary Supplements for Brain Health. Journal of the American Medical Association (JAMA) 2019 ;Volume 321.(24) p. 2467-
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41 Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Tell, Grethe S.; Nygård, Ottar; Mccann, Adrian; Ueland, Per Magne; Midttun, Øivind; Meyer, Klaus; Vedeler, Christian A.; Aarsland, Dag; Refsum, Helga; Smith, A. David; Melvær, Giil Lasse.
The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study. Brain, Behavior, and Immunity 2019 ;Volume 75. p. 155-162
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42 Su, Yi; Elshorbagy, Amany; Turner, Cheryl; Refsum, Helga; Chan, Ruth; Kwok, Timothy.
Circulating amino acids are associated with bone mineral density decline and ten-year major osteoporotic fracture risk in older community-dwelling adults. Bone 2019 ;Volume 129. p. 1-8
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2018
43 Allen, Lindsay H.; Miller, Joshua W.; de Groot, Lisette; Rosenberg, Irwin H.; Smith, A. David; Refsum, Helga; Raiten, Daniel J..
Biomarkers of Nutrition for Development (BOND): Vitamin B-12 Review. Journal of Nutrition 2018 ;Volume 148.(4) p. 1995S-2027S
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44 Elshorbagy, Amany; Samocha-Bonet, D.; Jernerén, Fredrik; Turner, Cheryl; Refsum, Helga; Heilbronn, Leonie K..
Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain. Journal of Nutrition 2018 ;Volume 148.(7) p. 1073-1080
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45 Olsen, Thomas; Vinknes, Kathrine; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Dhar, Indu; Tell, Grethe S.; Blomhoff, Rune; Ueland, Per Magne; Midttun, Øivind; Refsum, Helga; Nygård, Ottar.
The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A. European Journal of Preventive Cardiology (EJPC) 2018 ;Volume 25.(15) p. 1612-1620
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46 Olsen, Thomas; Øvrebø, Bente; Turner, Cheryl; Bastani, Nasser Ezzatkhah; Refsum, Helga; Vinknes, Kathrine.
Combining Dietary Sulfur Amino Acid Restriction with Polyunsaturated Fatty Acid Intake in Humans: A Randomized Controlled Pilot Trial. Nutrients 2018 ;Volume 10.(12) p. 1-15
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47 Smith, A. David; Refsum, Helga; Bottiglieri, Teodoro; Fenech, Michael; Hooshmand, Babak; McCaddon, Andrew; Miller, Joshua W.; Rosenberg, Irwin H.; Obeid, Rima.
Homocysteine and Dementia: An International Consensus Statement. Journal of Alzheimer's Disease 2018 ;Volume 62.(2) p. 561-570
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48 Sollie, Ove; Jeppesen, Per Bendix; Tangen, Daniel S.; Jernerén, Fredrik; Nellemann, Birgitte; Valsdottir, Thorhildur; Madsen, Klavs; Turner, Cheryl; Refsum, Helga; Skålhegg, Bjørn Steen; Ivy, John L.; Jensen, Jørgen.
Protein intake in the early recovery period after exhaustive exercise improves performance the following day. Journal of applied physiology 2018 ;Volume 125.(6) p. 1731-1742
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49 Wanders, Anne J.; Alssema, Marjan; De Hoon, Sabine E.M.; Feskens, Edith J.M.; van Woudenbergh, Geertruida J.; Van Der Kallen, Carla J.; Zock, Peter L.; Refsum, Helga; Drevon, Christian A; Elshorbagy, Amany; Schalkwijk, Casper G.; Stehouwer, Coen D. A.; Dekker, Jacqueline M.; Van Greevenbroek, Marleen M.J..
Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies. Annals of Nutrition and Metabolism 2018 ;Volume 72.(2) p. 117-125
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2017
50 Elshorbagy, Amany; Jernerén, Fredrik; Basta, Marianne; Basta, Caroline; Turner, Cheryl; Khaled, Maram; Refsum, Helga.
Amino acid changes during transition to a vegan diet supplemented with fish in healthy humans. European Journal of Nutrition 2017 ;Volume 56.(5) p. 1953-1962
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